The mechanochemical origins of the microtubule sliding motility within the kinesin-5 domain organization
S. Nithianantham, M. K. Iwanski, I. Gaska, H. Pandey, T. Bodrug, S. Inagaki, J. Major, G. J. Brouhard, L. Gheber, S. S. Rosenfeld, S. Forth, A. G. Hendricks, J. Al-Bassam
Molecular Biology of the Cell DOI:https://doi.org/10.1091/mbc.E23-07-0287 (2023)
bioRxiv DOI: DOI.org/10.1101/2021.10.12.463902
Directly measuring forces within reconstituted active microtubule bundles
J. Palumbo, E. Tai, S. Forth
Journal of Visualized Experiments 183 e6381 DOI:DOI: 10.3791/63819, (2022)
Two modes of PRC1-mediated mechanical resistance to kinesin-driven microtubule network disruption PubMed
A. Alfieri, I. Gaska, and S. Forth
Current Biology 31 DOI: DOI: 10.1016/j.cub.2021.03.034, (2021)
bioRxiv DOI: DOI: 10.1101/2020.08.10.244491, (2020)
The Mitotic Crosslinking Protein PRC1 Acts Like a Mechanical Dashpot to Resist Microtubule Sliding PubMed PDF
I. Gaska, M. Armstrong, A. Alfieri, and S. Forth
Developmental Cell 54 DOI: DOI: 10.1016/j.devcel.2020.06.017, (2020)
bioRxiv DOI: DOI: 10.1101/2019.12.12.874529, (2020)
Substrate–Enzyme Interactions in Intramembrane Proteolysis: γ-Secretase as the Prototype
X. Liu, J. Zhao, Y. Zhang, I. Ubarretxena-Belandia, S. Forth, R. L. Lieberman, and C. Wang
Frontiers in Molecular Neuroscience 13:65 DOI: 10.3389/fnmol.2020.00065, (2020)
The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding
Bodrug T., Wilson-Kubalek E.M., Nithianantham S., Thompson A.F., Alfieri A., Gaska I., Major J., Debs G., Inagaki S., Gutierrez P., Gheber L., McKenney R.J., Sindelar C.V., Milligan R., Stumpff J., Rosenfeld S.S., Forth S., Al-Bassam J.
eLife DOI: 10.7554/eLife.51131, (2020)
High-resolution imaging reveals how the spindle midzone impacts chromosome movement PubMed PDF
M.C. Pamula, L. Carlini, S. Forth, P. Verma, S. Suresh, W.R. Legant, A. Khodjakov, E. Betzig, and T.M. Kapoor
Journal of Cell Biology DOI: 10.1083/jcb.201904169, (2019)
The mechanics of microtubule networks in cell division PubMed PDF
S. Forth and T.M. Kapoor
Journal of Cell Biology DOI: 10.1083/jcb.201612064, (2017)
Measuring Pushing and Braking Forces Generated by Ensembles of Kinesin-5 Crosslinking Two Microtubules PubMed PDF
Y. Shimamoto*, S. Forth*, T.M. Kapoor (*co-first authors)
Developmental Cell 34, 669-681 (2015) --- Preview featured in Developmental Cell Press release from the Rockefeller University Newswire
Asymmetric Friction of Nonmotor MAPs Can Lead to Their Directional Motion in Active Microtubule Networks PubMed PDF
S. Forth, K.-C. Hsia, Y. Shimamoto, T.M. Kapoor
Cell 157, 420-432 (2014) --- Preview featured in Developmental Cell Press release from the Rockefeller University Newswire
Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends PubMed PDF
S.-C. Ti, M.C. Pamula, S.C. Howes, C. Duellberg, N.I. Cade, R.E. Kleiner, S. Forth, T. Surrey, E. Nogales and T.M. Kapoor
Developmental Cell 37, 72-84 (2016)
Reconstitution of the augmin complex provides insights into its architecture and function PubMed PDF
K.-C. Hsia, E.M. Wilson-Kubalek, A. Dottore, Q. Hao, K.-L. Tsai, S. Forth, Y. Shimamoto, R.A. Milligan, and T.M. Kapoor
Nature Cell Biology 16, 852-863 (2014)
Dynamic regulation of transcription factors by nucleosome remodeling PubMed PDF
M. Li, A. Hada, P. Sen, L. Olufemi, M.A. Hall, B.Y. Smith, S. Forth, J.N. McKnight, A. Patel, G.D. Bowman, B. Bartholomew, M.D. Wang
eLife 2015;4:e06249 (2015)
Torque Measurement at the Single Molecule Level PubMed PDF
S. Forth, M.Y. Sheinin, J.T. Inman, and M.D. Wang
Annual Review of Biophysics 42, 583-604 (2013)
Direct Measurements of Torque During Holliday Junction Migration PubMed PDF
S. Forth, C. Deufel, S.S. Patel, M.D. Wang
Biophysical Journal 100, L05-L07 (2011)
Underwound DNA under Tension: Structure, Elasticity, and Sequence-Dependent Behaviors PubMed PDF
M. Sheinin, S. Forth, J.F. Marko, and M.D. Wang
Physical Review Letters 107:108102 (2011)
Passive Torque Wrench and Angular Position Detection Using a Single Beam Optical Trap PubMed PDF
J. Inman*, S. Forth*, and M.D. Wang (*contributed equally to this work)
Optics Letters 35:17, 2949-51 (2010)
Discontinuities at the DNA Supercoiling Transition PubMed PDF
B. Daniels, S. Forth, M.Y. Sheinin, M.D. Wang and J.P. Sethna
Physical Review E 80:040901 (2009)
Abrupt Buckling Transition Observed during the Plectoneme Formation of Individual DNA Molecules PubMed PDF
S. Forth, C. Deufel, M.Y. Shienin, B. Daniels, J.P. Sethna and M.D. Wang
Physical Review Letters 100:148301 (2008)
Nanofabricated quartz cylinders for angular optical trapping: torque detection during DNA supercoiling PubMed PDF
C. Deufel, S. Forth, C.R. Simmons, S. Dejgosha and M.D. Wang
Nature Methods 4, 223-5 (2007)
Adsorption of CF4 on the Internal and External Surfaces of Opened Single-Walled Carbon Nanotubes: A Vibrational Spectroscopy Study PubMed PDF
O. Byl, P. Kondratyuk, S. Forth, S.A. Fitzgerald, L. Chen, J.K. Johnson and J.T. Yates, Jr.
Journal of the American Chemical Society 125, 5889 (2003)
Induced infrared absorption of molecular hydrogen in solid C60 PDF
S.A. Fitzgerald, S. Forth and M. Rinkoski
Physical Review B 65:140302 (2002)